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Regression of carotid stenoses after corticosteroid therapy in occlusive thromboaortopathy (Takayasu's disease).
Author(s) -
K. Ishikawa,
Yoshihiro Yonekawa
Publication year - 1987
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.18.3.677
Subject(s) - medicine , occlusion , angiography , vertebral artery , subclavian artery , stenosis , prednisolone , surgery , warfarin , common carotid artery , corticosteroid , radiology , carotid arteries , cardiology , atrial fibrillation
A 34-year-old, single Japanese woman with active Takayasu's disease presented with stenosed bilateral common carotid arteries, subtotal occlusion of the left subclavian artery, and complete occlusion of the ipsilateral proximal vertebral artery, as demonstrated by angiography. A right subclavian-left vertebral bypass using an autologous saphenous vein graft was successfully performed after 36 days of corticosteroid therapy. Subsequently, warfarin was administered in addition to prednisolone. After 32 months of treatment with a gradual reduction from 50 to 3.75 mg of prednisolone daily, angiography revealed a functioning bypass graft and regression of bilateral common carotid stenoses.

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