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Fatty acid pattern of red blood cell membranes and risk of ischemic brain infarction: a case-control study.
Author(s) -
Stefano Ricci,
L. Patoia,
Marco Berrettini,
L. Binaglia,
M G Scarcella,
Giampaolo Bucaneve,
Alba Vecchini,
I Carloni,
Lívia da Cunha Agostini,
Pas quale Parise
Publication year - 1987
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.18.3.575
Subject(s) - medicine , linoleic acid , red blood cell , stroke (engine) , ischemic stroke , fatty acid , brain cell , risk factor , cerebral infarction , red cell , brain infarction , blood lipids , membrane , endocrinology , ischemia , biochemistry , cholesterol , biology , mechanical engineering , engineering , microbiology and biotechnology
The fatty acid composition of red blood cell membranes (which reflects dietary fat intake) was studied in 28 male patients with recent (less than 3 days) ischemic stroke and 56 matched controls. Fifteen fatty acids were measured by means of chromatographic analysis. Percentages of linoleic, 22:5, and 22:6 acids were significantly lower in red blood cell membranes of stroke patients than in those of matched controls. The results suggest that a low unsaturated fatty acid diet could be an independent risk factor for ischemic brain infarction.

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