Open AccessAcute stroke therapy trials: an introduction to recurring design issues.
Author(s) -
Arnold B. Sterman,
A J Furlan,
Michael S. Pessin,
Carlos S. Kase,
Louis R. Caplan,
George W. Williams
Publication year - 1987
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.18.2.524
Subject(s) - medicine , stroke (engine) , concomitant , acute stroke , intensive care medicine , clinical trial , physical therapy , surgery , mechanical engineering , tissue plasminogen activator , engineering
We discuss selected issues concerning the design of stroke treatment trials. Key issues include the type of stroke studied, the time interval from stroke onset to patient entry, and whether to include cardioembolic strokes and allow concomitant therapy.
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