Measurement of cerebral blood flow during xenon inhalation as measured by the microspheres method. | Zendy

David Gur | Zendy; Howard Yonas | Zendy; David Jackson | Zendy; Sidney K. Wolfson | Zendy; Howard E. Rockette | Zendy; W F Good | Zendy; Glenn S. Maitz | Zendy; E.E. Cook | Zendy; Vincent C. Arena | Zendy

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Measurement of cerebral blood flow during xenon inhalation as measured by the microspheres method.

Author(s) -

David Gur,

Howard Yonas,

David Jackson,

Sidney K. Wolfson,

Howard E. Rockette,

W F Good,

Glenn S. Maitz,

E.E. Cook,

Vincent C. Arena

Publication year - 1985

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.16.5.871

Subject(s) - xenon , inhalation , microsphere , cerebral blood flow , medicine , blood flow , anesthesia , cerebrovascular circulation , nuclear medicine , biomedical engineering , chemistry , organic chemistry , chemical engineering , engineering

Measurements of cerebral blood flow (CBF) were performed using the microsphere technique in non-human primates (baboons) to assess the effect of non-radioactive xenon gas inhalation on CBF. Blood flows in small tissue volumes (approximately 1 cm3) were directly measured before and during the inhalation of xenon/oxygen gas mixtures. The results of these studies demonstrated that when inhaled in relatively high concentrations, xenon gas does increase CBF, but the changes are more global than tissue-specific. The problems and limitations of such evaluations are discussed.

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