Subarachnoid haemorrhage in the rat: angiography and fluorescence microscopy of the major cerebral arteries. | Zendy

T. Delgado | Zendy; J. Brismar | Zendy; N. Aa. Svendgaard | Zendy

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Subarachnoid haemorrhage in the rat: angiography and fluorescence microscopy of the major cerebral arteries.

Author(s) -

T. Delgado,

J. Brismar,

N. Aa. Svendgaard

Publication year - 1985

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.16.4.595

Subject(s) - medicine , cisterna magna , vasospasm , angiography , cerebral arteries , basilar artery , subarachnoid haemorrhage , subarachnoid hemorrhage , cerebral vasospasm , anesthesia , radiology , cerebrospinal fluid , aneurysm

A subarachnoid haemorrhage (SAH) in the rat was produced by the injection of blood via a previously implanted catheter connected to the cisterna magna. Repeated angiographical examinations of the vertebro-basilar arteries revealed a biphasic vasospasm with a maximal acute spasm at ten minutes and a maximal late spasm at two days after cisternal blood injection. Fluorescence microscopical examination of the major cerebral arteries at day two after the SAH revealed a reduction in the fluorescence intensity and in the number of histochemically visible sympathetic nerve terminals.

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