Open AccessA new model of bilateral hemispheric ischemia in the rat--three vessel occlusion model.
Author(s) -
Motonobu Kameyama,
Jirô Suzuki,
Reizo Shirane,
A Ogawa
Publication year - 1985
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/01.str.16.3.489
Subject(s) - medicine , ischemia , occlusion , basilar artery , carotid arteries , cardiology , blood flow , common carotid artery , animal model
A new model of bilateral hemispheric ischemia was created in the rat by occluding the common carotid arteries and the basilar artery; this resulted in consistent and severe impairment of the cerebral blood flow. The procedure for producing this model is described, and the results of EEG and autoradiography obtained by this model are compared to those obtained by the four-vessel occlusion model.
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