Intracranial internal carotid artery stenosis: longterm prognosis. | Zendy

D J Marzewski | Zendy; A J Furlan | Zendy; P Louis | Zendy; John R. Little | Zendy; Michael T. Modic | Zendy; G Williams | Zendy

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Intracranial internal carotid artery stenosis: longterm prognosis.

Author(s) -

D J Marzewski,

A J Furlan,

P Louis,

John R. Little,

Michael T. Modic,

G Williams

Publication year - 1982

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.13.6.821

Subject(s) - medicine , stenosis , stroke (engine) , cardiology , internal carotid artery , population , myocardial infarction , mortality rate , coronary artery disease , cerebral infarction , ischemia , mechanical engineering , environmental health , engineering

Sixty-six patients with greater than or equal to 50% stenosis of an intracranial internal carotid artery (IICA) were followed-up for an average of 3.9 years. Eighteen patients (27.3%) experienced ischemic events; 8 (12.1%) had isolated TIA and 10 (15.2%) a stroke. The observed stroke rate for patients 35 years and older are 13 times the expected infarction rate for a normal population. Patients with tandem extracranial stenosis had a greater risk of stroke than patients with isolated IICA stenosis. Thirty-three patients (50%) died during follow-up and 55% of all deaths were cardiac related. The observed 5 year survival rate was 60% compared to an expected rate of 87%. Patients with IICA stenosis had a higher risk of stroke and death compared to a previously reported referral population with ICA occlusion. IICA stenosis is a marker of extensive cerebrovascular and systemic atherosclerotic disease, especially coronary artery disease.

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