Hypertension and acute focal cerebral ischemia. Infarction and edema after occlusion of a middle cerebral artery in cats. | Zendy

Tōru Hayakawa | Zendy; Arthur G. Waltz | Zendy; Raymond L. Jacobson | Zendy

Open Access

Hypertension and acute focal cerebral ischemia. Infarction and edema after occlusion of a middle cerebral artery in cats.

Author(s) -

Tōru Hayakawa,

Arthur G. Waltz,

Raymond L. Jacobson

Publication year - 1979

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.10.3.263

Subject(s) - medicine , cats , ischemia , cerebral edema , infarction , cardiology , edema , occlusion , cerebral infarction , middle cerebral artery , stroke (engine) , cerebral arteries , anesthesia , myocardial infarction , mechanical engineering , engineering

Hypertension was produced in 8 cats by nephrectomy and wrapping the opposite kidney. Subsequent occlusion of one middle cerebral artery caused ischemic infarcts that were larger than those of 8 normotensive cats. The larger infarcts may have been caused by increases of ischemic cerebral edema resulting from changes in the cerebral endothelial barrier induced by hypertension. In addition to increasing the likelihood of strokes, hypertension in humans may predispose toward larger cerebral infarcts.

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