Scanning electron microscopic study of endothelial cells of cerebral arteries from spontaneously hypertensive rats. | Zendy

Fumitada Hazama | Zendy; Takashi Ozaki | Zendy; Shigeru Amano | Zendy

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Scanning electron microscopic study of endothelial cells of cerebral arteries from spontaneously hypertensive rats.

Author(s) -

Fumitada Hazama,

Takashi Ozaki,

Shigeru Amano

Publication year - 1979

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.10.3.245

Subject(s) - medicine , cerebral arteries , pathology , scanning electron microscope , anatomy , endothelium , cardiology , physics , quantum mechanics

Endothelial cells of the cerebral arterial system in spontaneously hypertensive rats were investigated by scanning electronmicroscopy and found to show progressive changes such as increased microvilli, numerous plasmalemmal pits, enlargement of the cells and well-developed marginal folds. Regressive changes, such as balloon-like protrusions and crater-like cave-ins, were also observed. Platelet adhesion to the injured endothelial surface of cerebral arteries was frequent. The significance of these changes in the development of hypertensive cerebrovascular lesions is discussed.

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