Gastrointestinal complication of high-dose corticosteroid therapy in acute cerebrovascular patients. | Zendy

Gian Andrea Ottonello | Zendy; Alessandra Primavera | Zendy

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Gastrointestinal complication of high-dose corticosteroid therapy in acute cerebrovascular patients.

Author(s) -

Gian Andrea Ottonello,

Alessandra Primavera

Publication year - 1979

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/01.str.10.2.208

Subject(s) - medicine , stroke (engine) , complication , corticosteroid , vascular disease , lesion , gastrointestinal bleeding , acute stroke , gastrointestinal disease , disease , surgery , gastroenterology , mechanical engineering , tissue plasminogen activator , engineering

Corticosteroids are commonly used in the treatment of stroke, although their clinical effectiveness has not been established. Side effects, especially gastrointestinal complications, occur in patients with cerebral disease. A necroscopy study of 124 patients investigated the occurrence of gastrointestinal lesions in patients with acute stroke treated with high-dose of corticosteroids compared to untreated patients with stroke and to patients dying from non-vascular neurological diseases. A significant relationship between the use of steroids and gastrointestinal lesion in strokes is demonstrated.

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