Properties of Hyperthyroid Rat Myocardium | Zendy

William V. Whitehorn | Zendy; William C. Ullrick | Zendy; B. R. Andersen | Zendy

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Properties of Hyperthyroid Rat Myocardium

Author(s) -

William V. Whitehorn,

William C. Ullrick,

B. R. Andersen

Publication year - 1959

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.7.2.250

Subject(s) - medicine , cardiology , cardiac muscle , refractory period , left ventricles , hormone , endocrinology , ventricle

Electric and mechanical properties of right and left ventricular muscle of hyperthyroid rats have been studied in vitro. Excitability was not modified but refractory period was lengthened in left ventricular muscle. Developed tension was significantly reduced in both ventricles, the greater reduction being on the right. The results suggest direct and disproportionate effects of thyroid hormone on right and left ventricular myocardium.

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