Further Observations on the Potentiation of Postnephrectomy Hypertension of the Dog by Dietary Protein

An assay procedure for the evaluation of dietary factors in renoprival hypertension over a short period is described. By means of this procedure dietary protein was found to potentiate renoprival hypertension of the dog. In the absence of dietary protein 2.5 mEq. sodium per kilogram per day was attended by a slight but significant elevation in the arterial pressure. The same level of hypertension was observed with fluid and sodium loading alone, dietary protein plus a lesser sodium intake, and dietary protein plus a greater sodium intake.