Open AccessInfluence of Modified Corticosteroids on Antitryptic Activity of Rat Serum
Author(s) -
William F. Blatt,
EDWARD H. SCHAEFER,
JOHN ZYLBER,
H. Jensen
Publication year - 1958
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.6.3.314
Subject(s) - cortisone , prednisone , prednisolone , endocrinology , medicine , chemistry
This report deals with the influence of cortisone, prednisolone, prednisone and 9 α-fluorocortisol acetate on the serum antitryptic activity of normal, splenectomized, adrenalectomized and adrenalectomized-splenectomized rats. Elevation of serum antitryptic activity was most consistent with 9α-fluorocortisol acetate administration. Prednisolone and prednisone proved less effective while cortisone-induced changes were of small magnitude.
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