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Sodium Polyethylene Sulfonate Effects on Serum Lipids and Blood Coagulation
Author(s) -
Peter T. Kuo,
F. THOMAS HOPKINS,
Harold A. Wurzel
Publication year - 1958
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.6.2.178
Subject(s) - heparin , coagulation , sulfonate , anticoagulant , drug , sodium , pharmacology , chemistry , lipoprotein , cholesterol , biochemistry , medicine , organic chemistry
This investigation was undertaken in view of the interest lately aroused in the association of plasma lipids with atherosclerosis. Observations on the antilipemic and anticoagulant activities in man of sodium polyethylene sulfonate, a new drug with heparin-like properties, are presented. Alteration of the serum lipoprotein patterns of these patients observed during the course of the drug administration is also described.

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