English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

We studied the effect of systolic pressure and volume changes on the end-systolic pressure at a fixed end-systolic volume in the left ventricle of excised, cross-circulated canine hearts. Instantaneous ventricular volume was controlled and both end-diastolic and end-systolic volumes were clamped, as preprogrammed by a volume servo pump system. Ventricular ejection was completed at the end of natural systole. When the onset and velocity of ejection were widely varied during contractions with a given set of end-diastolic and end-systolic volumes, the end-systolic pressure was little affected by the changes in the systolic pressure and volume under a stable contractile state. When the end-diastolic volume was increased from the isovolumic condition, the end-systolic pressure at the same end-systolic volume decreased (P < 0.05) from the peak isovolumic pressure by 5-14%, for an ejection fraction of 40-70%. When the end-systolic volume was decreased while the end-diastolic volume was fixed, the end-systolic pressure decreased in proportion to end-systolic volume. These results were interpreted to indicate that, when ejection ends at the end of systole, stroke volume of the ventricle with a given end-diastolic volume is determined predominantly by the end-systolic pressure rather than by the entire systolic courses of the pressure and volume, drc Res 44; 238-249, 1979

circulation research

End-systolic pressure determines stroke volume from fixed end-diastolic volume in the isolated canine left ventricle under a constant contractile state.