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Histochemical Evaluation of Canine Coronary Artery and Aortic Lesions Induced by Intravenous Allylamine
Author(s) -
Loyal L. Conrad,
I. E. Gonzalez,
W. Joel,
R. H. Furman
Publication year - 1956
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.4.3.263
Subject(s) - allylamine , coronary arteries , aorta , artery , glycogen , lesion , polysaccharide , medicine , chemistry , biochemistry , pathology , polyelectrolyte , organic chemistry , polymer
The early lesions of the coronary arteries and aorta in animals given intravenous allylamine are described and are noted to be characterized by glycogen accumulation and by ground substance change indicated by increased PAS-positive material present after incubation with diastase. It is suggested that heterogeneous polysaccharides and/or substances containing 1–2 glycol linkages, other than sulphated acid polysaccharides, may be of importance in the early lesion.

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