The Acute Effects of Elimination of the Moderator Reflexes Upon Cardiac Output and Total Peripheral Resistance in the Anesthetized Dog | Zendy

Matthew N. Levy | Zendy; Shirley H. Brind | Zendy; FREDERICK R. BRANDLIN | Zendy

Open Access

The Acute Effects of Elimination of the Moderator Reflexes Upon Cardiac Output and Total Peripheral Resistance in the Anesthetized Dog

Author(s) -

Matthew N. Levy,

Shirley H. Brind,

FREDERICK R. BRANDLIN

Publication year - 1955

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.3.4.415

Subject(s) - peripheral resistance , vasomotor , reflex , vasoconstriction , denervation , cardiac output , medicine , anesthesia , blood pressure , peripheral , cardiology , vascular resistance , constriction , hemodynamics

The abrupt rise in mean arterial pressure resulting from elimination of the moderator reflexes is not accompanied by a significant increase in cardiac output. The acute hypertension is therefore attributed to a severe generalized vasoconstriction. The severity of this vasomotor response progressively diminishes during the interval immediately following denervation.

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