Open AccessTissue Permeability--a Factor in Atherogenesis
Author(s) -
ChunI Wang,
Louis E. Schaefer,
D. Adlersberg
Publication year - 1955
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.3.3.293
Subject(s) - cortisone , cholesterol , medicine , endocrinology , hyaluronidase , chemistry , biology , biochemistry , enzyme
Cortisone has a retarding effect on atherogenesis in cholesterol-fed rabbits, despite higher plasma cholesterol levels. This effect of cortisone is prevented by administration of hyaluronidase. The latter intensifies atherosclerosis and deposition of cholesterol in the liver.
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