The Limits of Right Ventricular Compensation Following Acute Increase in Pulmonary Circulatory Resistance | Zendy

Arthur C. Guyton | Zendy; A. W. Lindsey | Zendy; John J. Gilluly | Zendy

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The Limits of Right Ventricular Compensation Following Acute Increase in Pulmonary Circulatory Resistance

Author(s) -

Arthur C. Guyton,

A. W. Lindsey,

John J. Gilluly

Publication year - 1954

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.2.4.326

Subject(s) - circulatory system , cardiology , ventricle , constriction , medicine , pulmonary artery , vascular resistance , reflex , circulatory failure , anesthesia , hemodynamics

The ability of the right ventricle to compensate as the pulmonary artery is constricted appears to be determined by four major factors: (1) there occurs the well-known increased force of contraction as the right heart becomes distended; (2) the adequacy of the coronary circulation determines to a great extent the Degrees of pulmonary arterial constriction which can occur before failure occurs; (3) the circulatory reflexes apparently aid the compensation to a moderate extent; and (4) the greater the blood volume, the greater is the limit of compensation before right ventricular failure occurs.

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