The Pattern of Recovery of Renal Function Following Renal Artery Occlusion in the Dog | Zendy

Sydney M. Friedman | Zendy; Robert L. Johnson | Zendy; Constance L. Friedman | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Pattern of Recovery of Renal Function Following Renal Artery Occlusion in the Dog

Author(s) -

Sydney M. Friedman,

Robert L. Johnson,

Constance L. Friedman

Publication year - 1954

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.2.3.231

Subject(s) - medicine , ischemia , renal ischemia , renal function , renal artery , clamp , occlusion , kidney , renal blood flow , anesthesia , cardiology , surgery , reperfusion injury , mechanical engineering , clamping , engineering

The pattern of recovery of renal function following two hours of complete ischemia was studied in a series of dogs. A marked functional ischemia persisted for several hours after release of the clamp, but restoration of blood flow was substantially complete in 24 hours. Other renal functions returned slowly over a period of weeks, reflecting the rate of repair of damaged tubules. Two important phases of recovery are thus to be considered: (a) a brief but significant period of continuing ischemia immediately following the trauma, and (b) a period of slow repair of those nephrons damaged but not destroyed in the first phase of the insult.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research