Electrocardiographic Effects of Cortisone and Related Compounds on the Dog | Zendy

Rosè Lubschez | Zendy; Melville G. Magida | Zendy; NORMA PlKE | Zendy

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Electrocardiographic Effects of Cortisone and Related Compounds on the Dog

Author(s) -

Rosè Lubschez,

Melville G. Magida,

NORMA PlKE

Publication year - 1954

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.2.2.123

Subject(s) - cortisone , endocrinology , medicine , repolarization , excretion , chemistry , phosphate , urinary system , biochemistry , electrophysiology

Infusion of cortisone and related compounds in the normal dog under standardized conditions resulted in increased voltage and peaking of the T wave of the electrocardiogram. These alterations were not associated with significant changes in the plasma electrolytes. Plasma inorganic phosphate decreased and urinary phosphate excretion increased. Cortisone appears to alter ventricular repolarization, but the mechanism of the effect is unknown.

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