The Effect of Dihydrocholesterol on the Absorption of Cholesterol by the Rat | Zendy

Ray H. Rosenman | Zendy; Sanford O. Byers | Zendy; Meyer Friedman | Zendy

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The Effect of Dihydrocholesterol on the Absorption of Cholesterol by the Rat

Author(s) -

Ray H. Rosenman,

Sanford O. Byers,

Meyer Friedman

Publication year - 1954

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.2.1.45

Subject(s) - cholic acid , cholesterol , medicine , endocrinology , lymph , absorption (acoustics) , chemistry , pathology , materials science , composite material

Simultaneous feeding of dihydrocholesterol and cholesterol to rats significantly reduced the amount of cholesterol absorbed into the thoracic lymph. Hypercholesteremia and hyperphospholipemia developed in rats simultaneously fed cholesterol and cholic acid for 8 weeks. The addition of dihydrocholesterol to this diet also decreased the rate of development and magnitude of the hypercholesteremia, but had no apparent effect upon the rise of plasma phospholipids.

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