Open AccessEffect of Cortisone and ACTH on Blood Pressure of Hypotensive, Potassium-Deficient Rats
Author(s) -
Simon Freed,
Ray H. Rosenman,
Shirley St. George,
Malcolm K. Smith
Publication year - 1954
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.2.1.41
Subject(s) - cortisone , endocrinology , potassium , medicine , adrenal cortex , blood pressure , chemistry , organic chemistry
Potassium deficiency, induced in a series of rats by dietary deprivation, was associated with a depressor response. The administration of cortisone and, to a lesser extent, of corticotropin (ACTH), promptly elevated their lowered blood pressures. The possible participation of the adrenal cortex in the depressor response to potassium deficiency is discussed.
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