Open AccessPacemaker Activity During Vagal Escape Rhythms
Author(s) -
Andrew G. Wallace,
Willard M. Daggett
Publication year - 1964
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.15.2.93
Subject(s) - rhythm , asystole , atrioventricular node , cardiac pacemaker , sinoatrial node , heart rate , bundle , electrical conduction system of the heart , medicine , cardiology , anesthesia , electrocardiography , blood pressure , tachycardia , materials science , composite material
In dogs, bipolar electrograms were recorded from the SA node and His bundle to localize pacemaker sites during vagal escape and to study the effects of isoproterenol on escape mechanisms. Vagal escape can result from the development of pacemaker activity above the A-V node, within the region of the A-V node, and below the common bundle of His. Isoproterenol shortened the period of asystole prior to the onset of vagal escape, increased the rate of escape rhythms at all pacemaker sites, and occasionally changed the pacemaker to a higher focus in the conduction system.
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