Autoregulation of tissue blood flow in essential hypertension. | Zendy

Sean Blake | Zendy; Hilary M. Carey | Zendy; A. J. McShane | Zendy; T Walley | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Autoregulation of tissue blood flow in essential hypertension.

Author(s) -

Sean Blake,

Hilary M. Carey,

A. J. McShane,

T Walley

Publication year - 1985

Publication title -

hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.986

H-Index - 265

eISSN - 1524-4563

pISSN - 0194-911X

DOI - 10.1161/01.hyp.7.6.1003

Subject(s) - autoregulation , vasodilation , vasoconstriction , vascular resistance , blood flow , mechanism (biology) , homeostasis , peripheral , medicine , peripheral resistance , cardiology , blood pressure , cardiac output , philosophy , epistemology

Autoregulation of tissue blood flow is a mechanism by which tissues control their own blood supply. The mechanism is dependent on an intrinsic capacity of tissues to vary their arteriolar resistance in relation to their needs. One view of the nature of the increased peripheral resistance in essential hypertension is that it represents autoregulatory vasoconstriction functioning to hold in check a cardiac output that would otherwise be excessive; in this situation autoregulation would be functioning normally. An alternative view is that the increased peripheral resistance represents the effect of a direct-acting vasoconstrictor substance; in this situation autoregulation would be rendered defective in its vasodilator capacity. A study of autoregulatory vasodilatation in eight subjects with essential hypertension supported an autoregulatory mechanism as the cause of the increased peripheral resistance.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research