The role of calcium in genetic hypertension.
Author(s) -
Kai Lau,
Bonnie Eby
Publication year - 1985
Publication title -
hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.986
H-Index - 265
eISSN - 1524-4563
pISSN - 0194-911X
DOI - 10.1161/01.hyp.7.5.657
Subject(s) - medicine , vitamin d and neurology
T HE importance of the calcium ion in muscle contractility and in the optimal functions of the cardiovascular and neurological systems has been recognized since the time of Ringer. A huge body of research data has been generated investigating various facets of the control of blood pressure, including the role of calcium in the biochemistry and physiology of contractile proteins. Interests have been renewed over the past decade on the role of calcium in genetic hypertension at the molecular as well as the organ or whole organism level. Many recent observations on this subject in humans with essential hypertension and in the rat model of spontaneous hypertension are of potential scientific and clinical interest. This review is an attempt to critically analyze the pertinent available data with the following objectives in mind:
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