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Effect of dietary sodium reduction on red blood cell sodium concentration and sodium-lithium countertransport.
Author(s) -
Richard Cooper,
Maurizio Trevisan,
Linda Van Horn,
Emmanuel Larbi,
K Liu,
Serafim Nanas,
Hirotsugu Ueshima,
Christopher T. Sempos,
David G. Ostrow,
Jeremiah Stamler
Publication year - 1984
Publication title -
hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.986
H-Index - 265
eISSN - 1524-4563
pISSN - 0194-911X
DOI - 10.1161/01.hyp.6.5.731
Subject(s) - sodium , lithium (medication) , dietary sodium , medicine , endocrinology , chemistry , red blood cell , intracellular , low sodium diet , biochemistry , blood pressure , renin–angiotensin system , organic chemistry
A randomized, crossover trial was carried out on the effect of moderate sodium reduction on red-blood-cell sodium metabolism. The participants were healthy high school students (mean age = 16 years, n = 33). Changes in sodium-lithium countertransport and intracellular sodium concentration were evaluated 24 days after a decrease in dietary sodium from approximately 110 to 40 mEq per day. Dietary sodium restriction had no significant effect on either sodium-lithium countertransport or intracellular sodium concentration.

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