Effect of captopril on renal hemodynamics in the treatment of resistant renal hypertension. | Zendy

S Björck | Zendy; Hans Herlitz | Zendy; G. Nyberg | Zendy; Göran Granérus | Zendy; Mattias Aurell | Zendy

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Effect of captopril on renal hemodynamics in the treatment of resistant renal hypertension.

Author(s) -

S Björck,

Hans Herlitz,

G. Nyberg,

Göran Granérus,

Mattias Aurell

Publication year - 1983

Publication title -

hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.986

H-Index - 265

eISSN - 1524-4563

pISSN - 0194-911X

DOI - 10.1161/01.hyp.5.5_pt_2.iii152

Subject(s) - captopril , medicine , filtration fraction , renal function , effective renal plasma flow , renal blood flow , renovascular hypertension , blood pressure , diabetic nephropathy , hemodynamics , urology , plasma renin activity , kidney , essential hypertension , nephropathy , aldosterone , cardiology , endocrinology , renin–angiotensin system , diabetes mellitus

The effects of 6 weeks of treatment with captopril on the renal hemodynamics of 16 patients with treatment-resistant renal hypertension (six had diabetic nephropathy, seven had other renal parenchymatous disease, and three had renovascular disease) were studied. Significant changes in glomerular filtration rate, filtration fraction, plasma renin activity, urinary aldosterone, and mean blood pressure were noted in the patients with renal parenchymatous disease, but not in those with diabetic nephropathy. Renal blood flow remained unchanged in all patients. Captopril was well tolerated.

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