Increase in plasma renin in aggressive mice originates from kidneys, submaxillary and other salivary glands, and bites. | Zendy

Knud Poulsen | Zendy; E. B. Pedersen | Zendy

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Increase in plasma renin in aggressive mice originates from kidneys, submaxillary and other salivary glands, and bites.

Author(s) -

Knud Poulsen,

E. B. Pedersen

Publication year - 1983

Publication title -

hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.986

H-Index - 265

eISSN - 1524-4563

pISSN - 0194-911X

DOI - 10.1161/01.hyp.5.2.180

Subject(s) - renin–angiotensin system , saliva , plasma renin activity , submaxillary gland , endocrinology , medicine , stimulation , kidney , submandibular gland , salivary gland , blood pressure

Aggressive behavior in mice caused a vast release of renin into the plasma. The present data support previous findings that the main sources were the submaxillary gland and kidney. In addition, unidentified salivary glands capable of releasing renin into the saliva were demonstrated by alpha-adrenergic stimulation. The role of these glands in generating plasma renin is unknown. Experiments were performed that strongly support the possibility that aggression-provoked salivary renin may be transferred by bites from one animal to another.

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