Ischemic cardiovascular complications concurrent with administration of captopril. A clinical note.
Author(s) -
Kenneth M. Baker,
D W Johns,
C R Ayers,
Robert M. Carey
Publication year - 1980
Publication title -
hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.986
H-Index - 265
eISSN - 1524-4563
pISSN - 0194-911X
DOI - 10.1161/01.hyp.2.1.73
Subject(s) - captopril , medicine , discontinuation , propranolol , myocardial infarction , angina , cardiology , ace inhibitor , ramipril , coronary artery disease , pindolol , angiotensin converting enzyme , blood pressure
Administration of potent vasodepressor agents such as the angiotensin converting enzyme inhibitor, captopril, may precipitate myocardial ischemic events in patients with coronary artery disease, particularly if this treatment is preceded by a discontinuation of beta-blocking drugs such as propranolol. In one case studied, a patient experienced three episodes of angina pectoris under these conditions; in another, acute anterior myocardial infarction was suspect.
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