Plasma norepinephrine variations with dietary sodium intake. | Zendy

M. Gary Nicholls | Zendy; Wolfgang Kiowski | Zendy; Andrew J. Zweifler | Zendy; Stevo Julius | Zendy; M. Anthony Schork | Zendy; Joel B. Greenhouse | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Plasma norepinephrine variations with dietary sodium intake.

Author(s) -

M. Gary Nicholls,

Wolfgang Kiowski,

Andrew J. Zweifler,

Stevo Julius,

M. Anthony Schork,

Joel B. Greenhouse

Publication year - 1980

Publication title -

hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.986

H-Index - 265

eISSN - 1524-4563

pISSN - 0194-911X

DOI - 10.1161/01.hyp.2.1.29

Subject(s) - endocrinology , norepinephrine , medicine , plasma renin activity , sodium , epinephrine , excretion , catecholamine , chemistry , urine , supine position , urine sodium , renin–angiotensin system , blood pressure , dopamine , organic chemistry

Plasma catecholamine and renin activity levels were measured across a range of dietary sodium intakes (10--300 mEq/day) in 20 normal male volunteers. Supine plasma norepinephrine levels presented a triphasic pattern in relation to urine sodium, whereas epinephrine levels were not significantly altered by sodium intake, and renin showed the well-known hyperbolic relationship to urine sodium excretion. Highest supine norepinephrine values occurred at low salt intakes, the lowest when sodium excretion was between 100 and 180 mEq/day, and intermediate when sodium excretion was greater than 180 mEq/day. These findings show that sodium intake is an important consideration in the interpretation of plasma norepinephrine levels.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research