Hypertension, non-insulin-dependent diabetes, and intracellular sodium metabolism. | Zendy

M. Trevisan | Zendy; Olga Vaccaro | Zendy; Martino Laurenzi | Zendy; Francesco De Chiara | Zendy; Mendoza Muro | Zendy; Roberto Iacone | Zendy; Adriana Franzese | Zendy

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Hypertension, non-insulin-dependent diabetes, and intracellular sodium metabolism.

Author(s) -

M. Trevisan,

Olga Vaccaro,

Martino Laurenzi,

Francesco De Chiara,

Mendoza Muro,

Roberto Iacone,

Adriana Franzese

Publication year - 1988

Publication title -

hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.986

H-Index - 265

eISSN - 1524-4563

pISSN - 0194-911X

DOI - 10.1161/01.hyp.11.3.264

Subject(s) - medicine , endocrinology , diabetes mellitus , intracellular , insulin , sodium , cotransporter , metabolism , essential hypertension , blood pressure , chemistry , biochemistry , organic chemistry

The present study was designed to investigate whether non-insulin-dependent diabetic hypertensive patients exhibit abnormalities in intracellular sodium metabolism similar to those described for essential hypertensive patients. Both normotensive and hypertensive non-insulin-dependent diabetic patients had similar average values of both Na+-Li+ countertransport and Na+-K+ cotransport compared with nondiabetic controls. Within the group of diabetic patients, hypertensive patients did not exhibit any abnormalities in either of the sodium transport pathways studied. The possible implications of these findings are addressed.

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