Open AccessRelationship Between Na + -Ca 2+ –Exchanger Protein Levels and Diastolic Function of Failing Human Myocardium
Author(s) -
Gerd Hasenfuß,
Wolfgang Schillinger,
Stephan E. Lehnart,
Michael Preuß,
Burkert Pieske,
Lars S. Maier,
Jürgen Prestle,
Kazutomo Minami,
Hanjörg Just
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.5.641
Subject(s) - diastole , medicine , endocrinology , calcium , endoplasmic reticulum , stimulation , diastolic function , chemistry , biochemistry , blood pressure
In the failing human heart, sarcoplasmic reticulum (SR) calcium handling is impaired, and therefore, calcium elimination and diastolic function may depend on the expression of sarcolemmal Na+-Ca2+ exchanger.
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