Heterogeneity of Coronary Flow Reserve in the Examination of Multiple Individual Allograft Coronary Arteries
Author(s) -
Thomas Wolford,
Thomas J. Donohue,
Richard G. Bach,
John H. Drury,
Eugene A. Caracciolo,
Morton J. Kern,
Leslie W. Miller
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.5.626
Subject(s) - medicine , coronary flow reserve , cardiology , univariate analysis , cardiac catheterization , fractional flow reserve , perfusion , coronary arteries , heart failure , multivariate analysis , coronary artery disease , artery , coronary angiography , myocardial infarction
Epicardial and resistance vessel function in the transplanted heart has been evaluated primarily in regions supplied by a single vessel. Heterogeneity of flow among multiple perfusion fields as a marker of early endothelial dysfunction in the microcirculation has not been evaluated previously. This study tested the hypothesis that increased variability of coronary flow reserve (CFR) among multiple vascular regions would be associated with allograft coronary vasculopathy.
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