PDGFβ Receptor Blockade Inhibits Intimal Hyperplasia in the Baboon | Zendy

Charles E. Hart | Zendy; Larry W. Kraiss | Zendy; Selina Vergel | Zendy; Debra G. Gilbertson | Zendy; Richard D. Kenagy | Zendy; Thomas R. Kirkman | Zendy; David L. Crandall | Zendy; Simon Tickle | Zendy; Helene M. Finney | Zendy; Geoff T Yarranton | Zendy; Alexander W. Clowes | Zendy

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PDGFβ Receptor Blockade Inhibits Intimal Hyperplasia in the Baboon

Author(s) -

Charles E. Hart,

Larry W. Kraiss,

Selina Vergel,

Debra G. Gilbertson,

Richard D. Kenagy,

Thomas R. Kirkman,

David L. Crandall,

Simon Tickle,

Helene M. Finney,

Geoff T Yarranton,

Alexander W. Clowes

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.4.564

Subject(s) - intimal hyperplasia , medicine , baboon , heparin , restenosis , lesion , platelet derived growth factor , angioplasty , growth factor , platelet derived growth factor receptor , pathology , receptor , smooth muscle , stent

We have evaluated the use of a mouse/human chimeric anti-platelet-derived growth factor-beta receptor antibody in combination with heparin to inhibit intimal hyperplasia in the saphenous artery of the baboon after balloon angioplasty.

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