Association Between Myocardial Infarction and the Mast Cells in the Adventitia of the Infarct-Related Coronary Artery
Author(s) -
Petri Laine,
Maija Kaartinen,
Antti Penttilä,
Pertti Panula,
Timo Paavonen,
Petri T. Kovanen
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.3.361
Subject(s) - adventitia , medicine , chymase , coronary arteries , tryptase , myocardial infarction , artery , histamine , cardiology , left coronary artery , mast cell , infarction , pathology , immunology
Histamine, a product of mast cells, is an effective vasoconstrictor of atherosclerotic coronary arteries. Because it has been suggested that coronary spasm plays a role in acute coronary syndromes such as myocardial infarction (MI), we quantified and characterized the mast cells in the adventitia of infarct-related coronary arteries.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom