Shed Membrane Microparticles With Procoagulant Potential in Human Atherosclerotic Plaques | Zendy

Ziad Mallat | Zendy; Bénédicte Hugel | Zendy; Jeanny Ohan | Zendy; Guy Lesèche | Zendy; JeanMarie Freyssinet | Zendy; Alain Tedgui | Zendy

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Shed Membrane Microparticles With Procoagulant Potential in Human Atherosclerotic Plaques

Author(s) -

Ziad Mallat,

Bénédicte Hugel,

Jeanny Ohan,

Guy Lesèche,

JeanMarie Freyssinet,

Alain Tedgui

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.3.348

Subject(s) - phosphatidylserine , tissue factor , thrombogenicity , annexin , apoptosis , prothrombinase , annexin a5 , microparticle , microbiology and biotechnology , thromboplastin , programmed cell death , cell , factor vii , medicine , phospholipid , immunology , chemistry , biology , thrombin , biochemistry , platelet , membrane , coagulation , astrobiology

The specific role of apoptosis in human atherosclerosis remains unknown. During apoptotic cell death, phosphatidylserine exposure on the cell surface confers a high tissue-factor (TF)-dependent procoagulant activity.

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