Prospective Evaluation of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism and the Risk of Stroke | Zendy

Robert Y.L. Zee | Zendy; Paul M. Ridker | Zendy; Meir J. Stampfer | Zendy; Charles H. Hennekens | Zendy; Klaus Lindpaintner | Zendy

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Prospective Evaluation of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism and the Risk of Stroke

Author(s) -

Robert Y.L. Zee,

Paul M. Ridker,

Meir J. Stampfer,

Charles H. Hennekens,

Klaus Lindpaintner

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.3.340

Subject(s) - medicine , prospective cohort study , stroke (engine) , diabetes mellitus , genotype , allele , angiotensin converting enzyme , relative risk , polymorphism (computer science) , endocrinology , genetics , gene , blood pressure , confidence interval , biology , mechanical engineering , engineering

The D/I polymorphism of the ACE gene has been studied in relation to a variety of cardiovascular disorders, including stroke. A number of small studies have been conducted, with inconsistent results. We investigated the association between ACE genotype and the incidence of stroke in a large, prospective, matched case-control sample from the Physicians' Health Study.

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