Open AccessOpening of Potassium Channels
Author(s) -
Egidijus Kėvelaitis,
Jacqueline Peynet,
Christian Mouas,
JeanMarie Launay,
Philippe Menasché
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.23.3079
Subject(s) - medicine , potassium channel , potassium , organic chemistry , chemistry
The tolerance of hibernating mammals to cold hypoxia is related to a factor similar to agonists of delta-opioid receptors. This study was designed to assess whether activation of these receptors could reproduce the protection conferred by ischemic preconditioning and whether such cardioprotection was similarly mediated by an opening of ATP-sensitive potassium (KATP) channels.
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