Open AccessThe Contribution of Activated Factor XIII to Fibrinolytic Resistance in Experimental Pulmonary Embolism
Author(s) -
Guy L. Reed,
Aiilyan K. Houng
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.2.299
Subject(s) - factor xiiia , fibrin , fibrinolysis , factor xiii , medicine , fibrinogen , tissue plasminogen activator , plasminogen activator , coagulation , immunology , pathology , endocrinology
The resistance of thrombi to fibrinolysis induced by plasminogen activators remains a major impediment to the successful treatment of thrombotic diseases. This study examines the contribution of activated factor XIII (factor XIIIa) to fibrinolytic resistance in experimental pulmonary embolism.
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