Tracheal Aspirate as a Substrate for Polymerase Chain Reaction Detection of Viral Genome in Childhood Pneumonia and Myocarditis | Zendy

Noorullah Akhtar | Zendy; Jiyuan Ni | Zendy; Daniel Stromberg | Zendy; Geoffrey L. Rosenthal | Zendy; Neil E. Bowles | Zendy; Jeffrey A. Towbin | Zendy

Open Access

Tracheal Aspirate as a Substrate for Polymerase Chain Reaction Detection of Viral Genome in Childhood Pneumonia and Myocarditis

Author(s) -

Noorullah Akhtar,

Jiyuan Ni,

Daniel Stromberg,

Geoffrey L. Rosenthal,

Neil E. Bowles,

Jeffrey A. Towbin

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.15.2011

Subject(s) - medicine , polymerase chain reaction , pneumonia , myocarditis , virology , genome , gene , cardiology , genetics , biology

Infectious respiratory disorders are important causes of childhood morbidity and mortality. Viral causes are common and may lead to rapid deterioration, requiring mechanical ventilation; myocardial dysfunction may accompany respiratory decompensation. The etiologic viral diagnosis may be difficult with classic methods. The purpose of this study was to evaluate polymerase chain reaction (PCR) as a diagnostic method for identification of causative agents.

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