Prior Cytomegalovirus Infection and the Risk of Restenosis After Percutaneous Transluminal Coronary Balloon Angioplasty | Zendy

C. Manegold | Zendy; Marwan Jabr Alwazzeh | Zendy; H Jablonowski | Zendy; Ortwin Adams | Zendy; Martin Medve | Zendy; Beate Seidlitz | Zendy; Ulrich E. Heidland | Zendy; Dieter Häussinger | Zendy; B. E. Strauer | Zendy; M. P. Heintzen | Zendy

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Prior Cytomegalovirus Infection and the Risk of Restenosis After Percutaneous Transluminal Coronary Balloon Angioplasty

Author(s) -

C. Manegold,

Marwan Jabr Alwazzeh,

H Jablonowski,

Ortwin Adams,

Martin Medve,

Beate Seidlitz,

Ulrich E. Heidland,

Dieter Häussinger,

B. E. Strauer,

M. P. Heintzen

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.10.1290

Subject(s) - medicine , restenosis , cardiology , angioplasty , coronary arteries , serostatus , stenosis , balloon , human cytomegalovirus , risk factor , atherectomy , cytomegalovirus , revascularization , artery , stent , myocardial infarction , viral load , viral disease , herpesviridae , human immunodeficiency virus (hiv) , immunology , virus

Restenosis is a common problem after all revascularization procedures in atherosclerotic coronary arteries. Reactivated human cytomegalovirus (CMV) has been detected in tissues of restenotic vascular lesions and was hypothesized to be a contributing pathogenic factor. Recent data suggest an association of restenosis after optimal coronary atherectomy with CMV serostatus, and a possible role of antiviral therapy was discussed. We therefore tested the hypothesis that prior CMV infection might be a risk factor for restenosis after conventional coronary balloon angioplasty (PTCA).

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