Sustained Improvement in Flow-Mediated Vasodilation After Short-Term Administration of Dobutamine in Patients With Severe Congestive Heart Failure | Zendy

M. B. Patel | Zendy; Ilya V. Kaplan | Zendy; Rajiv Patni | Zendy; Daniel Levy | Zendy; Joel A. Strom | Zendy; Jamshid Shirani | Zendy; Thierry H. LeJemtel | Zendy

Open Access

Sustained Improvement in Flow-Mediated Vasodilation After Short-Term Administration of Dobutamine in Patients With Severe Congestive Heart Failure

Author(s) -

M. B. Patel,

Ilya V. Kaplan,

Rajiv Patni,

Daniel Levy,

Joel A. Strom,

Jamshid Shirani,

Thierry H. LeJemtel

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.1.60

Subject(s) - dobutamine , medicine , brachial artery , heart failure , vasodilation , cardiology , discontinuation , reactive hyperemia , hemodynamics , anesthesia , skeletal muscle , blood pressure

In patients with severe congestive heart failure (CHF), short-term administration of dobutamine exerts sustained clinical benefits that are partially mediated by a training-like effect on skeletal muscle. Recently, physical training has been shown to enhance endothelial function in the skeletal muscle vasculature by improving endothelial function. Whether the dobutamine-induced training effect is also associated with an improvement in endothelial function in the skeletal muscle vasculature is currently unknown.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research