Treatment With Growth Hormone Enhances Contractile Reserve and Intracellular Calcium Transients in Myocytes From Rats With Postinfarction Heart Failure | Zendy

Minori Tajima | Zendy; Ellen O. Weinberg | Zendy; Jozef Bartúnek | Zendy; Hongkui Jin | Zendy; Renhui Yang | Zendy; Nicholas F. Paoni | Zendy; Beverly H. Lorell | Zendy

Open Access

Treatment With Growth Hormone Enhances Contractile Reserve and Intracellular Calcium Transients in Myocytes From Rats With Postinfarction Heart Failure

Author(s) -

Minori Tajima,

Ellen O. Weinberg,

Jozef Bartúnek,

Hongkui Jin,

Renhui Yang,

Nicholas F. Paoni,

Beverly H. Lorell

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.99.1.127

Subject(s) - medicine , heart failure , intracellular , calcium , myocyte , calcium in biology , cardiology , endocrinology , hormone , microbiology and biotechnology , biology

Recombinant human growth hormone (GH) improves in vivo cardiac function in rats with postinfarction heart failure (MI). We examined the effects of growth hormone (14 days of 3.5 mg. kg-1. d-1 begun 4 weeks after MI) on contractile reserve in left ventricular myocytes from rats with chronic postinfarction heart failure.

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