Nitric Oxide Synthase Is the Mediator of Late Preconditioning Against Myocardial Infarction in Conscious Rabbits
Author(s) -
Hitoshi Takano,
Srinivas Manchikalapudi,
XianLiang Tang,
Yumin Qiu,
Ali A. Rizvi,
Asad K. Jadoon,
Qin Zhang,
Roberto Bolli
Publication year - 1998
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.98.5.441
Subject(s) - medicine , nitric oxide synthase , coronary occlusion , sonomicrometry , nitric oxide , ischemic preconditioning , myocardial infarction , occlusion , nitroarginine , cardioprotection , myocardial stunning , anesthesia , infarction , cardiology , fissipedia , endocrinology , ischemia
Despite intense investigation, the effector of the infarct-limiting protection observed during the late phase of ischemic preconditioning (PC) remains unknown. The goal of this study was to test the hypothesis that late PC against myocardial infarction is mediated by the activity of nitric oxide synthase (NOS).
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