Spontaneous Variability of Left Ventricular Outflow Tract Gradient in Hypertrophic Obstructive Cardiomyopathy | Zendy

Ali M. Kizilbash | Zendy; Sheila K. Heinle | Zendy; Paul Grayburn | Zendy

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Spontaneous Variability of Left Ventricular Outflow Tract Gradient in Hypertrophic Obstructive Cardiomyopathy

Author(s) -

Ali M. Kizilbash,

Sheila K. Heinle,

Paul Grayburn

Publication year - 1998

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.97.5.461

Subject(s) - ventricular outflow tract , medicine , cardiology , pressure gradient , hypertrophic cardiomyopathy , coefficient of variation , diastole , stenosis , doppler echocardiography , blood pressure , statistics , physics , mathematics , mechanics

Improvement in the left ventricular outflow tract (LVOT) gradient has been used as a means of assessing response to therapy in patients with hypertrophic obstructive cardiomyopathy (HOCM). To our knowledge, no data exist regarding the spontaneous day-to-day variability of the LVOT gradient in patients with HOCM. Defining the magnitude of such variability is critical to properly understand how much improvement in LVOT gradient must be present to invoke a therapeutic response.

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