Open AccessHydrogen Peroxide Induces Intracellular Calcium Oscillations in Human Aortic Endothelial Cells
Author(s) -
Qinghua Hu,
Stefano Corda,
Jay L. Zweíer,
Maurizio C. Capogrossi,
Roy C. Ziegelstein
Publication year - 1998
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.97.3.268
Subject(s) - hydrogen peroxide , intracellular , biophysics , calcium , calcium in biology , medicine , stimulation , biochemistry , endocrinology , chemistry , biology
Because the vascular endothelium is exposed to oxidant stress resulting from ischemia/reperfusion and from the products of polymorphonuclear leukocytes or monocytes, studies were performed to examine the effect of hydrogen peroxide (1 micromol/L to 10 mmol/L) on endothelial Ca2+ signaling.
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