Passive Smoking Induces Atherogenic Changes in Low-Density Lipoprotein
Author(s) -
Miia Valkonen,
Timo Kuusi
Publication year - 1998
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.97.20.2012
Subject(s) - medicine , passive smoking , low density lipoprotein , lipoprotein , cardiology , endocrinology , environmental health , cholesterol
According to the American Heart Association, passive smoking is an important risk factor for coronary heart disease (CHD), but the mechanisms underlying this association are not fully understood. We studied the acute effect of passive smoking on the factors that influence the development of CHD: the antioxidant defense of human serum, the extent of lipid peroxidation, and the accumulation of LDL cholesterol in cultured human macrophages, the precursors of foam cells in atherosclerotic lesions.
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