Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese. | Zendy

Keiko Nakai | Zendy; C Itoh | Zendy; Yoshinori Miura | Zendy; Kohei Hotta | Zendy; Takehiko Musha | Zendy; Tomonori Itoh | Zendy; Tomohisa Miyakawa | Zendy; Ryu Iwasaki | Zendy; K Hiramori | Zendy

Open Access

Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese.

Author(s) -

Keiko Nakai,

C Itoh,

Yoshinori Miura,

Kohei Hotta,

Takehiko Musha,

Tomonori Itoh,

Tomohisa Miyakawa,

Ryu Iwasaki,

K Hiramori

Publication year - 1994

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.90.5.2199

Subject(s) - genotype , angiotensin converting enzyme , allele , medicine , coronary artery disease , endocrinology , population , myocardial infarction , biology , genetics , gene , blood pressure , environmental health

The angiotensin I-converting enzyme (ACE) is a key component of the renin-angiotensin system thought to be important in the pathogenesis of hypertension and cardiovascular disease. Deletion polymorphism in the ACE gene may be a risk factor for myocardial infarction in the Caucasian population. However, this finding has not yet been investigated in the Japanese population.

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