Initial contact and subsequent adhesion of human neutrophils or monocytes to human aortic endothelial cells releases an endothelial intracellular calcium store.
Author(s) -
Roy C. Ziegelstein,
Stefano Corda,
Роберто Пили,
Antonino Passaniti,
David J. Lefer,
Jay L. Zweíer,
Aureliano Fraticelli,
M. C. Capogrossi
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.90.4.1899
Subject(s) - endothelial stem cell , endothelium , adhesion , intracellular , microbiology and biotechnology , cytosol , endoplasmic reticulum , intercellular adhesion molecule 1 , monocyte , cell adhesion , medicine , immunology , biology , chemistry , biochemistry , in vitro , organic chemistry , enzyme
Increases in both leukocyte and endothelial cytosolic free [Ca2+] may be involved in intercellular adhesion by regulating the affinity of surface adhesion molecules or by facilitating transendothelial leukocyte migration. The purpose of this study was to examine the effect of initial contact and subsequent adhesion of human neutrophils or monocytes on human aortic endothelial [Ca2+].
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